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Nitric oxide metabolites and oxidative stress in mild essential hypertension

2010

Many papers have showed non univocal data about oxidative stress status and nitric oxide metabolites in essential hypertension. Considering this preamble we examined the total antioxidant status (TAS), the lipid peroxidation (LP), expressed as thiobarbituric acid-reactive substances (TBARS), the stable end products of nitric oxide (NOx) and LP/NOx ratio in 25 subjects with untreated mild essential hypertension. The obtained data show a significant increase in TBARS (p < 0.001) and NOx (p < 0.001) in hypertensives and no variation in TAS and in TBARS/NOx ratio. None of these parameters was statistically related to the metabolic parameters or to the blood pressure values. The high level of li…

AdultMalemedicine.medical_specialtyAntioxidantPhysiologymedicine.medical_treatmentBlood PressureEssential hypertensionmedicine.disease_causeThiobarbituric Acid Reactive SubstancesAntioxidantsNitric oxideEssential hypertension.Lipid peroxidationchemistry.chemical_compoundPhysiology (medical)Internal medicinemedicineTBARSHumansNOxOxidate streNitric oxideHematologyMiddle Agedmedicine.diseaseOxidative StressBlood pressureEndocrinologychemistryBiochemistryHypertensionFemaleLipid PeroxidationCardiology and Cardiovascular MedicineOxidative stressClinical Hemorheology and Microcirculation
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